Présentation
Helene Ragot

Contact
Post-doctorante dans le laboratoire des maladies génétiques cutanées du Pr. Alain Hovnanian depuis 2018, mon projet de recherche porte sur les signatures moléculaires dans les carcinomes épidermoïdes cutanés survenant chez les patients atteints d’Epidermolyse Bulleuse Dystrophique Récessive. J’ai obtenu mon doctorat de « physiologie, pathologie et thérapeutiques » à l’Université Pierre et Marie Curie en 2016. Sous la direction du Dr. Jane-Lise Samuel (Université Paris Diderot) Paris Diderot et du Dr. Christos Chatziantoniou (UPMC), j’ai étudié l’implication de la voie Notch3/RBPJk dans le système cardiovasculaire adulte. De 2016 à 2018, j’ai travaillé en tant qu’Attachée temporaire d’enseignement et de recherche (CNU66) dans le laboratoire du Pr. Onnik Agbulut (Sorbonne Université). Mon axe de recherche était axé sur l’ingénierie tissulaire à partir de différents biomatériaux pour des applications thérapeutiques de l’insuffisance cardiaque.
Ressources & publications
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Journal (source)Proc. Natl. Acad. Sci. U.S.A.
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form ...
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Journal (source)Nat. Med.
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 a...
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Journal (source)Front Genet
Identification of an Endoglin Variant Associated With HCV-Related Liver Fibro...
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Journal (source)Proc. Natl. Acad. Sci. U.S.A.
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form ...
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Journal (source)PLoS ONE
Prevalence and risk factors for latent tuberculosis infection among healthcar...
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Journal (source)Proc. Natl. Acad. Sci. U.S.A.
Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Park...
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Journal (source)J. Exp. Med.
Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reacti...
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Journal (source)J. Exp. Med.
Inherited IL-18BP deficiency in human fulminant viral hepatitis.
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Journal (source)Proc. Natl. Acad. Sci. U.S.A.
Homozygosity for TYK2 P1104A underlies tuberculosis in about 1% of patients i...
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Journal (source)Nucleic Acids Res.
SeqTailor: a user-friendly webserver for the extraction of DNA or protein seq...
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Journal (source)Proc. Natl. Acad. Sci. U.S.A.
Blacklisting variants common in private cohorts but not in public databases o...
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Journal (source)Sci Immunol
Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous...
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Journal (source)Bioinformatics
PopViz: a webserver for visualizing minor allele frequencies and damage predi...
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Journal (source)Hum. Mol. Genet.
A purely quantitative form of partial recessive IFN-γR2 deficiency caused by ...
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Journal (source)Front Immunol
CDG: An Online Server for Detecting Biologically Closest Disease-Causing Gene...
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Journal (source)Sci Rep
An eQTL variant of ZXDC is associated with IFN-γ production following Mycobac...
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Journal (source)Hepatology
A new 3p25 locus is associated with liver fibrosis progression in human immun...
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Journal (source)Oncotarget
BRIP1 coding variants are associated with a high risk of hepatocellular carci...
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Journal (source)J. Infect. Dis.
Major Loci on Chromosomes 8q and 3q Control Interferon γ Production Triggered...
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Journal (source)PLoS ONE
Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- o...
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Journal (source)Sci Rep
An eQTL variant of ZXDC is associated with IFN-γ production following Mycobac...
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Journal (source)Lancet Infect Dis
Genetics of human susceptibility to active and latent tuberculosis: present k...
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Journal (source)Semin. Immunol.
Human genetics of infectious diseases: Unique insights into immunological red...
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Journal (source)Nat. Rev. Immunol.
A novel genetic architecture of infectious diseases.
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Journal (source)Proc. Natl. Acad. Sci. U.S.A.
Common homozygosity for predicted loss-of-function variants reveals both redu...
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Journal (source)Science
Auto-antibodies against type I IFNs in patients with life-threatening COVID-19.
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Journal (source)Science
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.
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Journal (source)J Exp Med
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever...
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Journal (source)Sci Immunol
Polyclonal expansion of TCR Vbeta 21.3+ CD4+ and CD8+ T cells is a hallmark o...
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Journal (source)Sci Immunol
Polyclonal expansion of TCR Vbeta 21.3+ CD4+ and CD8+ T cells is a hallmark o...
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Journal (source)Sci Immunol
Polyclonal expansion of TCR Vbeta 21.3+ CD4+ and CD8+ T cells is a hallmark o...
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Journal (source)Nat Med
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child.
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Journal (source)Nature
Human genetic and immunological determinants of critical COVID-19 pneumonia.
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Journal (source)J Exp Med
Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I...
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Journal (source)J Exp Med
Gain-of-function human UNC93B1 variants cause systemic lupus erythematosus an...